Messenger by Lois Lowry

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As one of the few people able to travel through the dangerous Forest, Matty must deliver the message of Village’s closing and try to convince Seer’s daughter to return with him before it’s too late

Once a utopian community that prided itself on its welcome to new strangers, Village will soon be closed to all outsiders

But Forest has become hostile to Matty as well, and he must risk everything to fight his way through it, armed only with an emerging power he cannot yet explain or understand

Synergism between Calmodulin-Dependent Protein Kinase and C-Kinase A key to understanding how cells display sustained responses to activation through the calcium messenger system has been the recognition that receptor activation leads to the production …

Messenger RNA (mRNA) degradation in eukaryotic cells is a regulated process that can determine the level of expression of a gene. In particular, the existence of highly unstable RNAs allows for rapid and precise reductions or elevations in transcript levels following …

Though only recently uncovered as a physiologic messenger, nitric oxide (NO) is increasingly appreciated as a major regulator in the nervous, immune, and cardiovascular systems. Besides mediating normal functions, NO has been implicated in pathophysiologic …

Although pharmacological data provide strong evidence for different types of opioid receptors (eg, mu, delta, and kappa), they share many common properties in their ability to couple to second messenger systems. All opioid receptor types are coupled to G-proteins …

A novel RNA form, a lariat RNA, is generated during the splicing of mRNA precursors. These RNAs have a circular component with an extending, tail and are formed by a branch where an adenosine residue is linked through:-a 2'-5'phosphodiester bond to the 5'end of the'" …

The phosphoinositides are minor phospholipids present in all eukaryotic cells. They are storage forms for messenger molecules that transmit signals across the cell membrane and evoke responses to extracellular agonists. The phosphoinositides break down to liberate …

Nitric oxide (NO) is a free radical gas, clearly distinct from nitrous oxide, N20, which is used as an anesthetic and is chemically stable. NO has long been known to occur in bacteria, but until about 4 years ago, there was no evidence for its biological functions in vertebrates …

▪ Abstract Alternative pre-mRNA splicing is a central mode of genetic regulation in higher eukaryotes. Variability in splicing patterns is a major source of protein diversity from the genome. In this review, I describe what is currently known of the molecular mechanisms that …

Purpose: To review the physiologic role of nitric oxide, an unusual messenger molecule that mediates blood vessel relaxation, neurotransmission, and pathogen suppression. Data Sources: A MEDLINE search of articles published from 1987 to 1993 that addressed nitric …

Carbon monoxide, an activator of guanylyl cyclase, is formed by the action of the enzyme heme oxygenase. By in situ hybridization in brain slices, discrete neuronal localization of messenger RNA for the constitutive form of heme oxygenase throughout the brain has been …

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